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The process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronuclei.
in vitro f. (IVF) a process whereby (usually multiple) ova are placed in a medium to which sperm are added for fertilization, the zygote thus produced then being introduced into the uterus and allowed to develop to term.
in vivo f. f. of a ripe egg within the distal fallopian tube of a fertile donor female (rather than in an artificial medium), for subsequent nonsurgical transfer to an infertile recipient.
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