fragment (frag´ment)

A small part broken from a larger entity.
acentric f. acentric chromosome
Brimacombe f. a ribonucleoprotein f. obtained by mild ribonuclease treatment of ribosomes.
butterfly f. a broad triangular f. that is commonly present in comminuted fractures of the diaphysis.
Fab f. the antigen-binding f. of an immunoglobulin molecule, consisting of both a light chain and part of a heavy chain.Fab piece;
Fc f. the crystallizable f. of an immunoglobulin molecule composed of part of the heavy chains and responsible for binding to antibody receptors on cells and the Clq component of complement.Fc piece;
Klenow f. carboxyl terminal fragment of DNA polymerase I, contains polymerase as well as 3´ -> 5´ exonuclease activity to edit out mismatches.
Okazaki f. a relatively short (100-1000 bp) fragment of DNA that is later joined by DNA ligase to allow for 3´ -> 5´ overall chain growth during replication.
one-carbon f. the formyl group or the methyl group that takes part in transformylation or transmethylation reactions; by means of these reactions, a group containing a single carbon atom is added to a compound being biosynthesized, adding a methyl group (as in thymidine formation), adding a hydroxymethyl group (as in serine biosynthesis), or closing a ring (as in purine formation).
two-carbon f. the acetyl group (CH3CO-) that takes part in transacetylation reactions with coenzyme A as carrier; commonly referred to as acetate or acetic acid, from which it is derived.


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