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inositol (in-o´si-tol, -tol)

1,2,3,4,5,6-Hexahydroxycyclohexane;a member of the vitamin B complex necessary for growth of yeast and of mice; absence from the diet causes alopecia and dermatitis in mice and "spectacle eyes" in rats. It occurs in a number of stereoisomeric forms: cis-, epi-, allo-, neo-, myo-, muco-, chiro-, and scyllo-inositols; the most abundant naturally occurring one is myo-inositol (usually meant when "inositol" occurs alone).antialopecia factor, cyclohexitol, inose, inosite, lipositol, mouse antialopecia factor;
i. niacinate hexanicotinoyl inositol;a peripheral vasodilator.
i. 1,3,4,5-tetraphosphate a phosphorylated derivative of i. formed from inositol 1,4,5-trisphosphate that causes Ca2+ entry into the cytosol from the extracellular medium; inactivated by hydrolysis to form inositol 1,3,4-trisphosphate.
i. 1,4,5-trisphosphate (IP3) a second messenger formed from phosphatidylinositol 4,5-bisphosphate; triggers the release of calcium ions from special vesicles of the endoplasmic reticulum; has a role in the activation of neutrophils.


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