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insufficiency (in-su-fish´en-se)

1. Lack of completeness of function or power. 2. incompetence (1) [L. in-, neg. + sufficientia, fr. sufficio to suffice]
acute adrenocortical i. severe adrenocortical i. when an intercurrent illness or trauma causes an increased demand for adrenocortical hormones in a patient with adrenal insufficiency due to disease or use of relatively large amounts of similar hormones as therapy; characterized by nausea, vomiting, hypotension, and frequently hyperthemia, hyponatremia, hyperkalemia, and hypoglycemia; can be fatal if untreated.addisonian crisis, adrenal crisis, Bernard-Sergent syndrome;
adrenocortical i. loss, to varying degrees, of adrenocortical function.hypocorticoidism;
aortic i. See valvular i.
cardiac i. heart failure (1)
chronic adrenocortical i. adrenocortical i. usually as the result of idiopathic atrophy or destruction of both adrenal glands by tuberculosis, an autoimmune process, or other diseases; characterized by fatigue, decreased blood pressure, weight loss, increased melanin pigmentation of the skin and mucous membranes, anorexia, and nausea or vomiting; without appropriate replacement therapy, it can progress to acute adrenocortical i.Addison's disease, addisonian syndrome, hyposupradrenalism, morbus Addisonii;
convergence i. that condition in which an esophoria or esotropia is more marked for far vision than for near vision.
coronary i. inadequate coronary circulation leading to anginal pain.coronarism (1) ;
divergence i. that condition in which an exophoria or exotropia is more marked for near vision than for far vision.
exocrine pancreatic i. lack of exocrine secretions of pancreas, due to destruction of acini, usually by chronic pancreatitis; lack of digestive enzymes from pancreas results in diarrhea, usually fatty (steatorrhea) because of lack of pancreatic enzymes.
hepatic i. defective functional activity of the liver cells.
latent adrenocortical i. adrenocortical i. not clinically evident but which can become severe if a sudden stress, such as an intercurrent acute illness, develops.
mitral i. See valvular i.
muscular i. failure of any muscle to contract with its normal force, especially such failure of any of the eye muscles.
myocardial i. heart failure (1)
parathyroid i. hypoparathyroidism
partial adrenocortical i. normal basal adrenocortical function with failure of adrenocortical reserve to respond to ACTH stimulation.
primary adrenocortical i. adrenocortical i. caused by disease, destruction, or surgical removal of the adrenal cortices.
pulmonary i. See valvular i.
pyloric i. patulousness of the pyloric outlet of the stomach, allowing regurgitation of duodenal contents into the stomach.
renal i. defective function of the kidneys, with accumulation of waste products (particularly nitrogenous) in the blood.
respiratory i. failure to adequately provide oxygen to the cells of the body and to remove excess carbon dioxide from them.
secondary adrenocortical i. adrenocortical i. caused by failure of ACTH secretion resulting from anterior pituitary disease or inhibition of ACTH production resulting from exogenous steroid therapy.
thyroid i. subnormal secretion of hormones by the thyroid gland. See also hypothyroidism.
tricuspid i. See valvular i.
uterine i. atony of the uterine musculature.
valvular i. valvular regurgitation
velopharyngeal i. anatomical or functional deficiency in the soft palate or superior constrictor muscle, resulting in the inability to achieve velopharyngeal closure.
venous i. inadequate drainage of venous blood from a part, resulting in edema or dermatosis.


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