molecule (mol´e-kyul)

The smallest possible quantity of a di-, tri-, or polyatomic substance that retains the chemical properties of the substance. [Mod. L. molecula, dim. of L. moles, mass]
accessory m.'s cell surface adhesion m.'s on T cells that are involved in binding of one cell to another cell or in signal transduction, e.g., CD4.
adhesion m.'s m.'s that are involved in T helper-accessory cell, T helper-B cell, and T cytotoxic-target cell interactions.
cell adhesion m. (CAM) proteins that hold cells together, e.g., uvomorulin, and hold them to their substrates, e.g., laminin.
chimeric m. a m. (usually a biopolymer) containing sequences derived from two different genes; specifically, from two different species. Cf. chimera.
endothelial-leukocyte adhesion m. (E-LAM) 115,000 Mr m. on the surface of endothelial cells that is involved in blood leukocyte attachment to vessel walls as well as emigration from the vessels into the tissues.
gram-molecule the amount of a substance with a mass in grams equal to its molecular weight; e.g., a m. of hydrogen weighs 2.016 g, that of water 18.015 g.
intercellular adhesion m.-1 (ICAM-1) a glycoprotein that is expressed on a variety of cells. It is the ligand for LFA-1 as well as the receptor for the rhinoviruses.


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