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quinine (kwI´nIn, -nen, kwin´-In, -en)
C20H24N2O23H2O;the most important of the alkaloids derived from cinchona; an antimalarial effective against the asexual and erythrocytic forms of the parasite, but having no effect on the exoerythrocytic (tissue) forms. It does not produce a radical cure of malaria produced by Plasmodium vivax, P. malariae, or P. ovale, but is used in the treatment of cerebral malaria and other severe attacks of malignant tertian malaria, and in malaria produced by chloroquine-resistant strains of P. falciparum; it is also used as an antipyretic, analgesic, sclerosing agent, stomachic, and oxytocic (occasionally), and in the treatment of atrial fibrillation, myotonia congenita, and other myopathies.
q. bisulfate the acid sulfate of q., very soluble in water.
q. carbacryclic resin See resin.
q. ethylcarbonate an almost tasteless form of q. that is poorly absorbed from the intestinal tract.
q. sulfate the most frequently prescribed salt of q.
q. and urea hydrochloride sclerosing agent for treatment of internal hemorrhoids, hydrocele, and varicose veins, containing not less than 58% and not more than 65% of anhydrous q.
q. urethan a mixture of urethan and q. hydrochloride; a sclerosing agent for the treatment of varicose veins.
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