quinuclidinyl benzilate (QNB)

quinuclidinyl benzilate (QNB) (kwin-u´-kli-di-nil ben´-zil-at)

A highly potent anticholinergic agent exhibiting 50- to 100-fold greater potency over atropine in binding with and blocking muscarinic cholinergic receptors. Originally developed as a potential military incapacitating agent, it is currently extensively used as a radioactive agent (usually tritiated -H3 -QNB) to identify and label muscarinic receptors in pharmacologic studies.


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