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One of a group of organic substances, present in minute amounts in natural foodstuffs, that are essential to normal metabolism; insufficient amounts in the diet may cause deficiency diseases. [L. vita, life, + amine]
v. A 1. any beta-ionone derivative, except provitamin A carotenoids, possessing qualitatively the biological activity of retinol; deficiency interferes with the production and resynthesis of rhodopsin, thereby causing night blindness, and produces a keratinizing metaplasia of epithelial cells that may result in xerophthalmia, keratosis, susceptibility to infections, and retarded growth; 2. the original v. A, now known as retinol.axerophthol;
v. A1 retinol
v. A2 dehydroretinol
v. A1 acid retinoic acid
v. A1 alcohol retinol
v. A aldehyde retinaldehyde
v. A2 aldehyde dehydroretinaldehyde
antiberiberi v. thiamin
antihemorrhagic v. v. K
antineuritic v. thiamin
antirachitic v.'s ergocalciferol (v. D2) and cholecalciferol (v. D3).
antiscorbutic v. ascorbic acid
antisterility v. v. E (2)
v. B a group of water-soluble substances originally considered as one v.
v. B1 thiamin
v. B2 1. riboflavin 2. obsolete term for a complex of folic acid, nicotinic acid, nicotinamide, pantothenic acid, and riboflavin.
v. B3 1. obsolete term for nicotinamide and/or nicotinic acid; 2. obsolete term for pantothenic acid.
v. B4 1. once believed to be a factor necessary for nutrition of the chick, now identified simply as certain essential amino acids and/or adenine; 2. obsolete term for adenine.
v. B5 once used to describe biological activities now ascribed to pantothenic acid or nicotinic acid.
v. B6 pyridoxine and related compounds (pyridoxal; pyridoxamine).
v. B12 generic descriptor for compounds exhibiting the biological activity of cyanocobalamin (cyanocob(III)alamin); the antianemia factor of liver extract that contains cobalt, a cyano group, and corrin in a cobamide structure. Several substances with similar formulas and with the characteristic hematinic action have been isolated and designated: B12a, hydroxocobalamin; B12b, aquacobalamin; B12c, nitritocobalamin; B12r, cob(II)alamin; B12s, cob(I)alamin; B12III, factors A and V1a (cobyric acid), and pseudovitamin B12. Vitamins B12a and B12b are known to be tautomeric compounds; B12b has been obtained from cultures of Streptomyces aureofaciens: B12c has been obtained from cultures of Streptomyces griseus and is distinguishable from B12 by differences in its absorption spectrum. The physiologically active v. B12 coenzymes are methylcobalamin and deoxyadenosinecobalamine. A deficiency of v. B12 is often associated with certain methylmalonic acidurias.animal protein factor, antianemic factor, antipernicious anemia factor (1), erythrocyte maturation factor, maturation factor, methylcobalamin;
v. BT carnitine
v. Bx p-aminobenzoic acid
v. B complex a pharmaceutical term applied to drug products containing a mixture of the B v.'s, usually B1, B2, B3, B5, and B6.
v. Bc conjugase an enzyme catalyzing the hydrolysis of the pteroylpolyglutamic acids to pteroylmonoglutamic acid, with consequent increase in vitamin activity; v. Bc is an obsolete term for folic acid.
v. B12 with intrinsic factor concentrate a combination of v. B12 with suitable preparations of the mucosa of the stomach or intestine of domestic animals used for food by humans.
v. C ascorbic acid
coagulation v. obsolete term for v. K.
v. D generic descriptor for all steroids exhibiting the biological activity of ergocalciferol or cholecalciferol, the antirachitic v.'s popularly called the "sun-ray v.'s." They promote the proper utilization of calcium and phosphorus, thereby producing growth in young children, together with proper bone and tooth formation; the sulfate, a water-soluble conjugate, is found in the aqueous phase of human milk; v. D1 is a 1:1 mixture of lumisterol and v. D2.
v. D2 ergocalciferol
v. D3 cholecalciferol
v. E 1. a-tocopherol 2. generic descriptor of tocol and tocotrienol derivatives possessing the biological activity of a-tocopherol; contained in various oils (wheat germ, cotton-seed, palm, rice) and whole grain cereals where it constitutes the nonsaponifiable fraction, also in animal tissue (liver, pancreas, heart) and lettuce; deficiency produces resorption or abortion in female rats and sterility in males.antisterility factor, antisterility v., fertility v;
v. F term sometimes applied to the essential unsaturated fatty acids, linoleic, linolenic, and arachidonic acids.
fat-soluble v.'s those v.'s, soluble in fat solvents (nonpolar solvents) and relatively insoluble in water, marked in chemical structure by the presence of large hydrocarbon moieties in the molecule; e.g., v.'s A, D, E, K.
fertility v. v. E (2)
v. G obsolete term for riboflavin.
v. H biotin [Ger, H for Haut, skin]
v. K generic descriptor for compounds with the biological activity of phylloquinone; fat-soluble, thermostable compounds found in alfalfa, hog liver, fish meal, and vegetable oils, essential for the formation of normal amounts of prothrombin.antihemorrhagic factor, antihemorrhagic v;
v. K1 , v. K1(20) phylloquinone
v. K2 , v. K2(30) menaquinone-6
v. K2(35) menaquinone-7
v. K3 menadione
v. K4 menadiol diacetate
v. K5 4-amino-2-methyl-1-naphthol;an antihemorrhagic v.
microbial v. a substance necessary for the growth of certain microorganisms, e.g., biotin, p-aminobenzoic acid.
v. P a mixture of bioflavonoids extracted from plants (especially citrus fruits). It reduces the permeability and fragility of capillaries and is useful in the treatment of certain cases of purpura that are resistant to v. C therapy. See also hesperidin, quercetin, rutin.capillary permeability factor, citrin, permeability v;
permeability v. v. P
v. PP nicotinic acid
v. U term given to a factor in fresh cabbage juice that encourages the healing of peptic ulcer; (3-amino-3-carboxypropyl)dimethylsulfonium chloride; a methionine derivative.
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