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wobble

wobble (wah´bl)

In molecular biology, unorthodox pairing between the base at the 5´ end of an anticodon and the base that pairs with it (in the 3´-position of the codon); thus, the anticodon 3´-UCU-5´ may pair with 5´-AGA-3´ (normal or Watson-Crick pairing) or with 5´-AGG-3´ (wobble). Wobble pairings can occur between the unusual base hypoxanthine and adenine, uracil, or cytosine, between uracil and guanine, and between guanine and uracil, when in the 5´-position of an anticodon. See also wobble base.

 

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