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configuration (kon-fig-yu-ra´shun)

1. The general form of a body and its parts. 2. In chemistry, the spatial arrangement of atoms in a molecule. The c. of a compound (e.g., a sugar) is the unique spatial arrangement of its atoms such that no other arrangement of these atoms is superimposable thereon with complete correspondence, regardless of changes in conformation (i.e., twisting or rotation about single bonds); change of c. requires breaking and rejoining of bonds, as in going from d to l c.'s of sugars. Cf. conformation.
cis c. 1. See cis- (4). 2. the property of two or more sites on the same molecule of DNA.


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